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‘Tension type headacheis the most common type of headache experienced by most of us in our life.
As with other 5-HT1 agonistssensations of tightnesspainpressureand heaviness in the precordiumthroatneck and jaw commonly occur after treatment with rizatriptan and are usually noncardiac in originHoweverif a cardiac origin is suspectedpatients should be evaluatedPatients shown to have CAD and those with Prinzmetal’s variant angina should not receive 5-HT1 agonists.
Rizatriptan binds with high affinity to human cloned 5-HT 1B and 5-HT 1D receptorsRizatriptan has a weak affinity for other 5-HT 1 receptor subtypes5-HT 1A5-HT 1E5-HT 1Fand the 5-HT 7 receptorbut has no significant activity at 5-HT 25-HT 3alphaand beta-adrenergicdopaminergichistaminergicmuscarinic or benzodiazepine receptors.
A migraineon the other handis also a type of a headache which results in an acute throbbing sensation in one part of your headUsuallymigraine headaches are highly painfulMigraine pain makes it difficult for a person to carry out his/her daily tasksSymptoms or signs associated with migraine attacks are:
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